Tighter Controls, Better Insight to Perfusion Processes

Harvest & Recovery

With increased use of perfusion processes and single-use technologies, biomanufacturers face challenges of high cell concentrations and uncontrolled batch production that may result in extra processing and bad cultures. Emerson’s automated management solutions can provide tighter control of perfusion processes and batch procedures, while improving operation integration, resource allocation, data collection, cell monitoring, and full batch traceability for optimal recovery/harvest processes.

Enhance biomanufacturing harvest/recovery through controlled, integrated solutions that provide useful data in real time.
Flexible Technologies for Evolving Biologic Therapies

Streamlined Harvest & Recovery for High-Yield Processes

Integrated technologies that support scalability, compliance, and consistent product recovery

In biotechnology manufacturing, harvest and recovery represent a critical handoff—removing biomass or cell debris while preserving valuable product components. Reliable process instrumentation, automated control, and cleanroom-compatible devices support this balance between efficiency and care. Scalable solutions enable both stainless steel and single-use implementations maintain batch consistency, minimize contamination risk, and meet rigorous industry standards. Whether separating cells or managing clarification steps, smart technology enhances throughput and confidence.

Automation and Control at the Core of Harvest & Recovery

Harvest & Recovery Solutions in Action

Efficient recovery starts with the right process controls. From gently transferring liquids to monitoring fill levels and driving agitation systems, intelligent technologies support both performance and regulatory expectations. Integrated automation platforms coordinate operations, while sensors and valves deliver actionable insight and responsive flow control. Across primary recovery steps—from centrifugation to filtration—these tools drive yield improvement and reproducibility.

Deliver Accurate Flow for Yield Optimization

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Inability to effectively manage flow during harvest and recovery stages of a biomanufacturing process can result in improper transfer of material among vessels, leading to product degradation or suboptimal yields. Inadequate flow control can also result in inefficient recovery processes that inhibit future purification steps. Emerson’s portfolio of flow control solutions features the latest valve and metering technology, as well as cutting-edge control systems for enhanced flow management.

What You Need to Know

Frequently Asked Questions (FAQs)

Explore insights into common harvest and recovery challenges in biotechnology workflows. Learn how Emerson’s solutions help ensure quality, reduce waste, and improve process reliability during this critical phase.

Harvest and recovery is the stage where cells or products are separated from the culture media and collected for downstream processing. It plays a vital role in maintaining yield and quality.

Real-time level sensing helps avoid overflow, ensures efficient tank usage, and minimizes manual intervention, improving throughput and reducing risk.

Gentle and uniform mixing prevents cell damage and supports even distribution, which is essential for effective clarification or filtration steps.

Automation enables consistent control of flow, level, and mixing parameters, reduces operator error, and enhances data traceability and compliance.

Emerson offers solutions such as flow meters, level transmitters, and bioprocess automation platforms to help optimize each stage of harvest and recovery.

Accurate flow control helps prevent shear stress, reduces product loss, and ensures consistent filter performance, all of which are critical for product purity and yield.